Severe anemia due to parvovirus B19 in a silver haired boy.

ABSTRACT

Griscelli syndrome (GS) is a rare autosomal recessive immunodeficiency disorder in which the affected children present with characteristic silvery‑white hairs. The hair microscopy of these children is characteristic and is helpful in differentiating GS from Chediak–Higashi syndrome which also presents with immunodeficiency and silver hairs. We report a 17‑month‑old boy with GS type 2 who presented with severe anemia. Bone marrow examination of the child suggested parvovirus B19 as the cause of severe anemia, which was later confirmed by DNA polymerase chain reaction