A Comparison of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to Hyperbaric Bupivacaine for Lower Limb Surgery: A Double Blind Controlled Study.

ABSTRACT

Background: The aim of this study is to compare the effects of Dexmedetomidine and Fentanyl as intrathecal adjuvant to Bupivacaine on the onset and duration of sensory and motor block in orthopaedic lower limb surgeries. Methods: Ninety patients of ASA status I and II posted for lower limb surgery were randomly divided into three groups. Group D was administered Hyperbaric Bupivacaine 15 mg + Dexmedetomidine 5μg in 0.5 ml normal saline, group F was administered Hyperbaric Bupivacaine 15 mg + Fentanyl 25 μg in 0.5 ml normal saline and group C were administered Hyperbaric Bupivacaine 15 mg plus in 0.5 ml normal saline. Duration and quality of sensory and motor block were assessed. Results: Sensory and motor block in-group D patients were longer than group F and C patients. Conclusion: Intrathecal dexmedetomidine when added to bupivacaine heavy (0.5%) provide better and prolonged analgesia in comparison to fentanyl.