Losartan Induced Angioedema – A Case Report.

ABSTRACT

Angiotensin converting enzyme inhibitors (ACE I) and angiotensin receptor blockers (ARBs) are commonly prescribed as antihypertensive drugs and they also show similar side effects. However ARBs are well tolerated than ACE I with low incidence of side effects. Both these classes of drugs can rarely cause angioedema but it is extremely rare with ARBs. The exact pathogenesis of angioedema with ARBs is not known but it has been postulated to be due to activation of complement system and or other pro inflammatory cytokines like prostaglandins and histamine. We report a case of 30 year old male patient who was taking losartan for control of blood pressure but presented with facial swelling and submandibular edema thus suggestive of losartan induced angioedema.