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Acute myeloid leukemia with t(4;12)(q12;p13): A morphological dilemma.
Indian J Pathol Microbiol ; 2016 Oct-Dec 59(4): 545-547
Artigo em Inglês | IMSEAR | ID: sea-179683
ABSTRACT
Cytogenetics has a pivotal role in risk stratification of acute myeloid leukemia (AML). We report a case of AML with a t(4;12)(q12;p13). To the best of our knowledge, there are about 24 cases of t(4;12) reported in AML which are usually misdiagnosed as lymphoproliferative disorders on morphological assessment. This case showed specific clinical, morphological, and immunophenotypic features such as (1) pseudo lymphoid morphology, (2) dysplasia in granulocytic series, (3) an immature immunophenotype with positivity for CD34 and CD117, and (4) poor treatment response.

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Idioma: Inglês Revista: Indian J Pathol Microbiol Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Idioma: Inglês Revista: Indian J Pathol Microbiol Ano de publicação: 2015 Tipo de documento: Artigo