Comparative Study of Two Sclerosants for Pleurodesis for Incurable Pleural Effusions and Pneumothorax.
Br J Med Med Res
;
2015; 10(12):1-9
Artigo
em Inglês
| IMSEAR
| ID: sea-181871
ABSTRACT
Background:
Pleurodesis is indicated in thoracic pathologies associated with pleural effusions or pneumothoraces resulting from incurable diseases and therefore risked with high chance of recurrenceObjective:
To compare the success rates of the oral forms of tetracycline and injectable form of cyclophosphamide as chemical pleurodesants in clinical practice. Materials andMethods:
Prospective study.Results:
There were 33 patients who underwent pleurodesis of 40 pleural spaces (bilateral in 7 patients) M F=12.3 (10 vs 23) Age range 15-80 years (mean= 49 years). The primary outcome measure was taken at four weeks post pleurodesis. This was the success rate of the pleurodesis which was taken as non-recurrence of pleural effusion or pneumothorax at four weeks. At one month, 16(80%) of the pleural spaces that underwent pleurodesis with tetracycline hydrochloride were free from recurrence which makes for 80% success rate and 20% (recurrence) failure rate for tetracycline. The equivalent figures for cyclophosphamide were 85% and 15% respectively.Conclusion:
The oral form of tetracycline and cyclophosphamide injection can give approximately same outcome as sclerosants for pleurodesis in appropriate patients.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
Br J Med Med Res
Ano de publicação:
2015
Tipo de documento:
Artigo
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