Comparative study between inj. Ketamine hcl-Midazolam hcl & inj. Fentanyl citrate- Midazolam hcl in Paediatric Patient for Procedural Sedation (RT/CT/MRI).
Artigo
em Inglês
| IMSEAR
| ID: sea-182135
ABSTRACT
Introduction:
Interaction with medical providers is stressful experience for children. Because of this stress and the anxiety, minor procedures often require mild to moderate sedation. Sedation of the paediatric patient is a process carefully planned by the anaesthesia provider while maintaining the heart rate, respiration & oxygen saturation levels at the patient's baseline values.Methodology:
We studied 80 patients of either sex aged 2-10 years of ASA grade-1 and 2, undergoing Radiation therapy, CT Scan and MRI. They were randomly allocated in two groups 40 each to compare the efficacy, safety, and tolerability of inj. Ketamine - Midazolam combination to inj. Fentanyl - Midazolam combination for sedation of children during Radiation Therapy (RT)/Computerised Tomography Scan (CT Scan)/Magnetic Resonance Imagine(MRI). Both the groups were given IV inj. Midazolam 0.05 mg/kg before giving IV inj. Ketamine 1 mg/kg in group 1 while IV inj. Fentanyl 2 pg/kg in group 2.Result:
In both groups after giving sedation, there were no significant changes in heart rate. Degree of sedation was better in group I than in group II. Recovery from sedation was more prolonged in group 1 than in group 2.Conclusion:
It was found that inj. Ketamine-Midazolam combination offers good sedation without compromising respiration but more prolonged recovery and higher incidence of post procedural vomiting, while inj. Fentanyl-Midazolam combination has lower sedation score and higher incidence of respiratory depression.
Texto completo:
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Índice:
IMSEAR (Sudeste Asiático)
Idioma:
Inglês
Ano de publicação:
2014
Tipo de documento:
Artigo
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