Polyherbal Formulation (Hairzone Solution) in the Management of Diffuse Hair Loss: Post Marketing Safety and Efficacy Study.

ABSTRACT

Hair loss is a common and distressing problem, affecting men and women of all the ages and ranging from a small bare patch to a more diffuse and obvious pattern. The purpose of this study is to evaluate the safety and efficacy of Hairzone solution in diffuse hair loss. Twenty-eight cases were included in the study according to the subject selection criteria. All the patients were advised to gently massage the solution into the scalp part by part, covering the whole area of the scalp and to rinse it in the morning. The response to therapy was evaluated at monthly intervals for a period of six months. The changes in various parameters from baseline values and the values at each visit for six months were evaluated statistically using Graph Pad Prism Version 4.03 for windows, Graph Pad Software, San Diego, California, United States. The criteria for evaluation were signs and symptoms such as reduction in hairfall by 1-minute combing test, reduction in associated symptoms like itching and overall impression. The study clearly demonstrated the beneficial effects of Hairzone solution in diffuse hair loss as evident by reduced hair fall by 1-minute combing test, in addition to decrease in itching. Hair loss was reduced in 21 of 28 patients. Further safety of the product was also substantiated by clinical parameters. Therefore, it can be concluded that Hairzone solution is safe and effective in the management of diffuse hair loss.