Methotrexate Induced Stevens Johnson Syndrome: A Rare Case Report
Artigo
| IMSEAR
| ID: sea-184015
ABSTRACT
Methotrexate (MTX) is a folic acid antagonist with cytotoxic and immunosuppressant activity andwith potent antirheumatic action. It is commonly a first choice Disease modifying antirheumatic drug (DMARD). There were some spurious reports of Adverse Drug Reaction (ADR) by this drug. Here we report a rare occurrence of Stevens-Johnson syndrome (SJS) / Toxic Epidermal Necrolysis (TEN) after the use of Methotrexate. Naranjo score for this adverse drug event was six, thereby making it a probable ADR. Symptomatic management of the patient was done and the offending drug was withdrawn. We are presenting this case to highlight the serious adverse reactions possible from a routinely prescribeddrug
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Índice:
IMSEAR (Sudeste Asiático)
Ano de publicação:
2019
Tipo de documento:
Artigo
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