A Retrospective Analysis of Prevalence of Uropathogens and Antibiotic Sensitivity Pattern in Patients of Urinary Tract Infection in a Tertiary Care Teaching Hospital

ABSTRACT

Background: Antibiotic Resistance has now become a big threat as antibiotics are no more useful now a days, as they were previously. The objective of this study was to analyse the various bacterial isolates found in Urinary Tract Infection. Methods: This Retrospective study was conducted in the department of Microbiology in collaboration with the department of Pharmacology of Pacific Medical College and Hospital, Udaipur, Around 705 culture proven urine isolates were retrospectively studied. The samples were collected during one year from both the inpatient as well as the outpatient department of Pacific Medical College and Hospital, Udaipur. Results: Uropathogenic strains from inpatient and outpatient departments were studied for their susceptibility profiles. The various isolates were Escherichia coli, Klebseilla pneumoniae, Pseudomonas aeruginosa. Antibiotic susceptibility pattern of these isolates revealed that for outpatients, first generation Cephalosporins, nitrofurantoin, Norfloxacin/ciprofloxacin were effective for treatment of urinary tract infection but for inpatients, parenteral therapy with newer aminoglycosides and third generation Cephalosporins should be administered as the organisms for nosocomial UTI exhibit a high degree of drug resistance. Conclusion: Culture and sensitivity of the isolates from urine samples should be done as a routine before starting the antimicrobial therapy.