Accuracy Of Single Progesterone Assay To Predict Early Pregnancy Outcome

ABSTRACT

OBJECTIVE: To study the accuracy of estimation of single serum progesterone level in predicting early pregnancy outcome in symptomatic women with inconclusive USG MATERIALAND METHODS: 70 women with gestational age less than 12 weeks fulfilling the inclusion criteria were included in the study. RESULTS: Out of 70 women, the follow up scan revealed 33 viable pregnancies and 37 non-viable pregnancies. Mean serum progesterone was significantly higher in viable pregnancy group (16.318± 7.29 ng/ml), compared with non-viable pregnancy group (8.07± 5.878ng/ml) and the association was found to be statistically significant with a ‘p’ value of 0.0001. Serum progesterone of 10ng/ml has sensitivity of 72.97% in predicting a non-viable pregnancy and specificity of 81.81% in predicting viable pregnancy. CONCLUSION: Single serum progesterone value of less than 10ng/ml can be a useful test in predicting early pregnancy failure in symptomatic patients with inconclusive USG.