A Comparative Prognostic Study of Acute Myocardial Infarction Thrombolysis in Diabetics Vs Non-Diabetics Using ECG as A Tool A Hospital Based Study

ABSTRACT

Background: Diabetes mellitus is one of the six primary risk factors identified for MI, others being dyslipidaemia, smoking, hypertension, male gender, and family history of atherosclerotic arterial disease. Diabetics have been shown to have poor outcome after post-thrombolysis in acute STEMI compared to non-diabetics. Objective: To Compare, Post Myocardial Infarction in Hospital Patients Prognosis After Thrombolytic Therapy In Diabetics versus Non-Diabetics. Materials and methods: This was a prospective cross sectional study done at Jhalawar Medical College and Hospital, Jhalawar on 139 patients from October 2016 to September 2017. Consecutive patients with ST segment elevation MI, who were not treated with primary angioplasty, but were thrombolysed with Streptokinase were recruited at the time of arrival in emergency department. ECG was taken at baseline and 2 hour after STK administration. Patients were divided in two groups A) Non-diabetics B) Diabetics. Total 139 patients 85 are diabetics and 54 are non-diabetics. Bhuvanesh Kumar Kahar, Sushma Pandey, Ankush Agrawal, Darab Singh, Ravindra Kumar Sharma. A Comparative Prognostic Study of Acute Myocardial Infarction Thrombolysis in Diabetics Vs Non-Diabetics Using ECG as A Tool – A Hospital Based Study. IAIM, 2018; 5(8) 41-46. Page 42 Results: In non-diabetic group (54), ST segment resolution occurred in 77.76 % patients as compared to diabetic group (85) in which only 31.76% patients had ST segment resolution. Diabetics had more complications such as recurrent chest pain, heart failure, arrhythmias, death as compared to nondiabetics. Conclusion: Diabetics with acute myocardial infarction have worse prognosis as predicted by incomplete ST segment resolution in ECG after thrombolysis.