Study on Clinico-Aetiological Profile of Bicytopenia / Pancytopenia among Pediatric Patients

ABSTRACT

The common causes of bicytopenia or pancytopenia include either marrow suppression or marrow infiltration. It may be due to aplastic anemia, megaloblastic anemia or hematological malignancies. The present study was done to find the clinico-aetiological profile of bicytopenia & pancytopenia among pediatric patients. Methods: The present hospital based cross-sectional study was done on children suffering from bicytopenia or pancytopenia. Detailed clinical history, thorough physical examination and hematological tests were done. Appropriate statistical calculations for summarization of data were done. Results: Bicytopenia was seen in 58.2% and pancytopenia in 41.8% patients. Megaloblastic anemia (43.6%), infection (23.6%), aplastic anemia (14.5%) and leukemia (10.9%) were the aetiological factors. Patients presented with pallor (85.5%), fever (76.4%), petechial haemorrhage (43.6%), hepatomegaly (38.2%), splenomegaly (23.6%), anorexia (21.8%) and lymphadenopathy (18.2%). Conclusion: Non-malignant causes were responsible in majority of cases (89.9%) and can be treated.