Effect of arteether alpha/beta on uncomplicated falciparum malaria cases in Upper Assam.
Artigo
em Inglês
| IMSEAR
| ID: sea-19203
ABSTRACT
Thirty patients of uncomplicated Plasmodium falciparum malaria completed a clinical trial of arteether alpha/beta conducted in a malaria endemic tea garden of district Dibrugarh, Assam. Arteether was given intramuscularly in once a day dose of 150 mg for three consecutive days. The cure rate was 100 per cent with mean fever and parasite clearance time of 42.4 +/- 17.5 and 37.6 +/- 13.6 h respectively. Recrudescence/reinfection rate was 6.7 per cent. Palpable spleens of twenty out of twenty one cases on day 0 became non palpable within 28 days. Following the treatment, percentage of hemoglobin improved marginally with no remarkable change in total and differential leucocyte count. Arteether alpha/beta, besides being a potent and fast acting schizontocidal drug, also exhibited gametocytocidal action on P. falciparum.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sesquiterpenos
/
Feminino
/
Humanos
/
Masculino
/
Adolescente
/
Malária Falciparum
/
Adulto
/
Artemisininas
/
Índia
/
Pessoa de Meia-Idade
País/Região como assunto:
Ásia
Idioma:
Inglês
Ano de publicação:
1996
Tipo de documento:
Artigo
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