Effect of zinc sulphate on infarct size in experimental myocardial infarction in dogs.
Artigo
em Inglês
| IMSEAR
| ID: sea-19560
ABSTRACT
The effect of zinc sulphate on myocardial infarct size following left coronary artery branch occlusion in dogs was studied. Zinc sulphate (10 mg/kg) was administered po, 24 h and 2 h before coronary occlusion in one group of animals. The area at risk was visualised by methylene blue injected intraventricularly. The infarcted area was visualised by triphenyl tetrazolium chloride staining. The infarct size expressed as a percentage of risk zone was 76.54 +/- 3.01 per cent (mean +/- SE) in the control group and 37.96 +/- 2.20 per cent in the zinc sulphate group (P less than 0.001). Zinc sulphate appears to be a potent prophylactic agent for limiting the size of myocardial infarct in the dogs.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Sulfatos
/
Zinco
/
Feminino
/
Masculino
/
Sulfato de Zinco
/
Cães
/
Animais
/
Infarto do Miocárdio
Idioma:
Inglês
Ano de publicação:
1991
Tipo de documento:
Artigo
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