Comparative evaluation of grading of breast carcinomas in fine needle aspirates by two methods.
Artigo
em Inglês
| IMSEAR
| ID: sea-19669
ABSTRACT
BACKGROUND & OBJECTIVES:
Fine needle aspiration (FNA) material is increasingly being used to determine various prognostic parameters in patients with carcinoma breast. It was recommended that cytological grading should be part of all FNA reports of breast carcinoma so that preoperative prognostication could be done on it. However, the most reliable method for cytological grading that closely reflects the most widely used histological grading system is yet to be determined. This study was undertaken to compare results of two cytological grading methods to see which corresponded better to the histological grade.METHODS:
In a double-blind study, cytological grading of 52 patients with breast carcinoma was carried out using two different grading systems (Robinson's and Mouriquand's methods) and the grades compared with the histological grading to find out which reflected histological grades more closely.RESULTS:
By Robinson's method 28.8, 46.2 and 25 per cent aspirates were graded as I, II and III respectively. Using Mouriquand's grading 9.6, 69.2 and 21.2 per cent aspirates were graded correspondingly. Comparison of the two methods showed a concordance in 40 (76.9%) cases. Both cytological grading systems showed a concordance of 71.2 per cent with the histological grading. Robinson's cytological grading showed a diagnostic accuracy of 80.76 per cent with 77.77 per cent specificity while Mouriquand's method had an accuracy of 84.60 per cent with 33.33 per cent specificity. INTERPRETATION &CONCLUSION:
Though the Robinson's and Mouriquand's grading systems were found to have similar concordance with histological grading, Robinson's method was considered better because of its simplicity, and specificity.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias da Mama
/
Feminino
/
Humanos
/
Método Duplo-Cego
/
Sensibilidade e Especificidade
/
Carcinoma Ductal
/
Biópsia por Agulha Fina
/
Erros de Diagnóstico
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo diagnóstico
/
Estudos de avaliação
/
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
2003
Tipo de documento:
Artigo
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