Buccal Mucosal Dna Damage Following Radiotherapy In Patients With Head And Neck Cancer

ABSTRACT

Patients with head and neck cancer receiving radiotherapy in addition to antitumour effects also are exposed toionizing radiation which may also damage normal tissue located in the field of radiation. The study was done onbuccal scrapings in patients with head and neck cancer patients receiving radiotherapy at the hospital. Thepresent study aims at determining the changes in MN in the buccal smears in pre and post RT in patients withhead and neck cancer patients. The mean number of MN was significantly high in buccal scrapings of patientspost RT suggesting DNA damage following exposure to radiations during RT.