In vitro & in vivo experimental susceptibility of Mycobacterium marinum to augmentin.
Artigo
em Inglês
| IMSEAR
| ID: sea-19847
ABSTRACT
The effect of augmentin alone and in combination with various beta-lactam antibiotics was studied against a pathogenic Mycobacterium, M. marinum. The in vitro studies did not reveal any additional advantage over that found with augmentin alone and this antibiotic seemed considerably inhibitory to M. marinum at < 1 microgram/ml concentration. In vivo, the effects of augmentin on experimentally produced lesions in the mouse foot pads (MFPs) showed a significant regression of the lesions, which was compatible with an early disappearance of M. marinum from the MFP, in contrast with those of the untreated, control animals.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Masculino
/
Testes de Sensibilidade Microbiana
/
Ácidos Clavulânicos
/
Combinação Amoxicilina e Clavulanato de Potássio
/
Quimioterapia Combinada
/
Amoxicilina
/
Animais
/
Camundongos
/
Mycobacterium
Idioma:
Inglês
Ano de publicação:
1996
Tipo de documento:
Artigo
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