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Non-vaccine Pneumococcal Serotypes Among Children with Invasive Pneumococcal Disease
Indian Pediatr ; 2018 Oct; 55(10): 874-876
Artigo | IMSEAR | ID: sea-199185
ABSTRACT

Objective:

To report the percentage of non-vaccine pneumococcal serotypes and theirantibiotic susceptibility pattern in children with invasive peumococcal disease.

Methods:

Invasive pneumococcal isolates of children <5 years during January 2007 to December2016 were serotyped by a co-agglutination reaction and sequential multiplex polymerasechain reaction.

Results:

Among the total 170 S. pneumoniae invasiveisolates, 54 (31.8%)and 44 (25.9 %) were the serotypes, which are not included in current 10-valent or 13-valent vaccines, respectively. Very low resistance was observed against penicillin (4.5%)and all isolates were susceptible to cefotaxime.

Conclusions:

One-fourth to one-third ofthe S. pneumoniae serotypes in under-five children with invasive pneumococcal diseaseare not covered by existing pneumococcal vaccines in India.

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Revista: Indian Pediatr Ano de publicação: 2018 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Revista: Indian Pediatr Ano de publicação: 2018 Tipo de documento: Artigo