Single Hepatitis B Booster Dose in High-risk Children with Suboptimal Surface Antigen Antibody Responses After 3-dose Primary Vaccine Series

ABSTRACT

This was a descriptive study of 30 children born to HBsAG positivemothers between June 2009 and December 2013. All childrenhad anti-HBs response ≤100 IU/L after 3 doses of hepatitis Bvaccine primary series. A single booster dose led to hepatitis Bsurface antibody titers ≥100 IU/L in (85%) of children.