Role of Citicoline for Management of Myopic Amblyopia Patients in Teriary Care Hospital of India

ABSTRACT

Introduction: Myopia is a very common condition affectingpeople worldwide. Current research aimed to study the effectsof oral citicoline as treatment option in myopic amblyopia.Material and Methods: Patients of myopic amblyopia ofage group 5-30 years were evaluated between June2018 toMarch2019. Detailed eye examinations including visualacuity, refraction, and dilated fundoscopy were done. Patientswere randomly divided into 2 groups. 1 group of patients weregiven oral citicoline(500mg) daily for 12 weeks. Other groupof patients was given placebo daily for 12 weeks. All patientswere followed up to at monthly interval for 6 months; visualacuity and refraction were done in each follow up visit.Results: Total 378 patients with myopic amblyopia wereidentified. Visual acuity improved or became stable overtime following citicoline therapy, as compared to placebo.Maximum improvement in visual acuity was from 6/60 to6/9(p).Conclusion: Citicoline therapy resulted in significantimprovement or stability of visual acuity in myopic amblyopicpatients.