Clinical Features of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Among Bangladeshi Patients in a Tertiary Care Center

ABSTRACT

To observe the clinical nature of ADPKD in Bangladeshipatients we studied 40 cases, among them 16 (40%) weremale and 24 (60%) female. A higher proportion of younger thanolder patients were affected (40% Vs 10%, P<0.05).Hypertension and loin pain was present in 30 (75%) and 22(55%) cases respectively. Renal function at presentation wasnormal in 20 (50%) cases, with mild to moderate and severerenal failure was present in 16 (40%) and 4 (10%) casesrespectively. Bilateral enlarged kidneys found in 30 (70%)cases. Size of kidneys varies from 12.1cm to 25.6cm. Multiplecysts in both kidneys were present in 36 (90%) patients, withhepatic and pancreatic cyst was present in 15 (37.5%) and 3(7.5%) cases respectively. Much younger patients arediagnosed as ADPKD in our population, so every effort shouldbe made for early diagnosis in suspected cases so that needfor dialysis may be reduced by retarding rate of progression byconservative measures.