Conventional Radiotherapy versus Accelerated Fractionation Radiotherapy in Squamous Cell Head and Neck Cancers – A Prospective Comparative Study
Artigo
| IMSEAR
| ID: sea-209227
ABSTRACT
Introduction:
Treatment of locally advanced lesions of head and neck cancers includes a combined modality approach suchas surgery, radiotherapy (RT), and chemotherapy.Aim:
The aim of the study was to study the treatment response by locoregional control and radiation toxicity of conventionaland accelerated fractionation RT in squamous cell head and neck cancers.Materials andMethods:
A total of 30 patients were included in each group, Group A received accelerated six fractions perweek and Group B received conventionally fractionated radiation therapy. The patients were assessed for locoregional diseaseresponse and radiation toxicities weekly during RT and at the end of treatment.Results:
In this study, 4 patients were dropped out and 26 patients completed the treatment in each group. About 86% of thepatients in the accelerated fractionation arm and 82% of the patients in conventional arm showed complete response. Radiationtoxicities were slightly higher in accelerated fractionation compared to conventional fractionation RT.Conclusion:
Accelerated fractionation with concurrent chemotherapy can be considered as an alternative treatment strategyto conventional chemoradiation.
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Índice:
IMSEAR (Sudeste Asiático)
Ano de publicação:
2019
Tipo de documento:
Artigo
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