Protection against Ultraviolet B Radiation-Induced Oxidative Damage by Antioxidants on Liver of Female Wistar rat
Artigo
| IMSEAR
| ID: sea-209333
ABSTRACT
Introduction:
Ultraviolet B (UVB) radiation exposures induced toxicity and generate oxidative stress on liver tissue and their alternative effect on biochemical process. Curcumin (Cur) and ascorbic acid (AA) act as a good antioxidant and shown the protective effect on animal tissue. Materials andMethods:
Twenty-four adult healthy female Wistar rats weighing 130–150 g were used. It is divided into four groups, the 1st group considers as control, the 2nd group considers as UVB treated, the 3rd group considers as UVB + Cur group, and the last 4th group considers as UVB + AA, exposure of radiation for 15 days.Results:
We found that UVB radiation shown on the female Wistar rat alteration on the animal body weight, liver weight, lipid peroxide, superoxide dismutase, and glutathione as compared to the control group.Conclusion:
It is concluded that UVB radiation shows the harmful effect on female Wistar rat and little preventive effect of Cur and AA.
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Índice:
IMSEAR (Sudeste Asiático)
Ano de publicação:
2020
Tipo de documento:
Artigo
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