Hyperemesis Gravidarum, Wernicke Encephalopathy and Korsakoff Syndrome: A Critical Appraisal of the Relevant Literature

ABSTRACT

Background: Hyperemesis g ravidarum tends to r apidly progressin to Wernicke encephal opathy and Korsak off syndromeand, therefore, need stoberecognizedearlyandmanagedpromptlywithtargetedmultimodaltherapies.Objective:Thisstudycriticallyreviewedtherelevantliteratureonclinicalperspectivesofhyperemesisgravidarum,WernickeencephalopathyandKorsakoffsyndrome.Thesecondaryobjectiveofthisstudywastoimprovetheawareness,emphasisonearlydiagnosisandimmediateinterventionconcerningthesesequentialsyndromesinpregnantwomenacrosstheboard.Methods:Electronicsearches(sinceinception-2019)ofPubMed/MEDLINE,GoogleScholar,OvidSP,DoveMedicalPress,ScienceDomainInternational(SDI)andHindawi.comwere