Low-cost monitoring of HIV infected individuals on highly active antiretroviral therapy (HAART) in developing countries.
Artigo
em Inglês
| IMSEAR
| ID: sea-21490
ABSTRACT
The standard methods to monitor HIV infection are flow cytometry-based for CD4+ T lymphocyte count and molecular assays to quantify plasma viral load of HIV. Few laboratories in resource-limited countries can run these tests as a majority of the HIV infected individuals are poor. A number of currently available low-cost assays which require less expensive equipment and reagents, may be well-suited to such countries. These include manual and ELISA based CD4 cell assays, and ultrasensitive reverse transcriptase quantitation (Cavidi) and p24 (ELAST) assays to monitor virus load. But better internal quality assurance and quality control (QA/QC) programmes are essential. This review discusses the low-cost assays and their role in clinical monitoring of HIV infected individuals in resource-limited countries like as India.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Ensaio de Imunoadsorção Enzimática
/
Biomarcadores
/
Infecções por HIV
/
Monitoramento de Medicamentos
/
Contagem de Linfócito CD4
/
Carga Viral
/
Terapia Antirretroviral de Alta Atividade
/
Países em Desenvolvimento
Tipo de estudo:
Guia de Prática Clínica
/
Avaliação Econômica em Saúde
Idioma:
Inglês
Ano de publicação:
2005
Tipo de documento:
Artigo
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