Protective Role of Foeniculum vulgare Mill. in Brain Disorders; A New Window
Artigo
| IMSEAR
| ID: sea-215836
ABSTRACT
Aims:
Alzheimer disease and epilepsy are two of the central nervous system (CNS) disorders that not only affect the quality of life of patients but also of family members and caretakers. Remedies for these illnesses are available in allopathic medicines but not without side effects. Herbal products are being investigated for these ailments. Protective role of Foeniculum vulgareMill. was assessed in this study. StudyDesign:
Laboratory based randomized controlled trial. Place and Duration of Study Conducted inPharmacology Department of University of Karachi, between March 2018 and April 2018Methodology:
Mice and rats were divided in three groups, control, 2% and 4% F. vulgaregroups, each containing 10 rodents. Control group was fed standard rodent diet, whereas, study groups were given 2% and 4% F. vulgareseeds (crushed) incorporated in standard rodent diet. Epilepsy model was made for mice and Alzheimer disease study was done using rats and passive avoidance test.Results:
Lower incidence of seizures and mortality in both study groups as compared to control in epilepsy model and memory retaining effect in both treated groups in Alzheimer disease model was recorded with statistical significance.Conclusion:
Clinical studies should be conducted to validate the protective role of this herb in these disorders
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Tipo de estudo:
Ensaio Clínico Controlado
Ano de publicação:
2020
Tipo de documento:
Artigo
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