Trigonella foenum-graecum Derived Phytochemicals against Cough

ABSTRACT

Phytochemicals from Trigonella foenum-graecum plant extract are traditionally used to cure Cough.There are many reasons for cough. It has been reported that cough can be caused as a result of Bordetella sp. infection. The objective of the study is to identify the phytochemical of Trigonella foenum-graecum capable of curing Cough. Molecular docking method applied using “Biovia Discovery Studio”. The research clearly indicates that choline, arginine, and gentianine cannot effectively deactivate the enzyme histidinekinase of the microbe. On the other hand, carpaine and diosgenin failed to deactivate the enzyme. Thus, none of these phytochemicals can effectively deactivate the histidinekinase enzyme of Bordetella sp. and thus cannot be used to treat cough caused by this particular microbe