Serum ferritin and glycated hemoglobin in type 2 diabetes mellitus: A case–control study

ABSTRACT

Background: High body iron stores have been linked to insulin resistance, metabolic syndrome, and gestational diabetes. Complications of diabetes mellitus are influenced not only by its duration but also by average level of blood glucose, the latter can be monitored by glycated hemoglobin. Aim and Objective: The aim of this study was to study the relationship of serum ferritin and glycated hemoglobin in type 2 diabetes mellitus. Materials and Methods: The case–control study was undertaken on 100 subjects, both males and females; age 35–70 years; categorized into two groups Group 1 (Cases = 50 patients of type 2 diabetes mellitus [T2DM]) and Group 2 (Controls = 50 healthy, non-diabetic individuals). Results: Fasting blood glucose, serum ferritin, and glycated hemoglobin values were 178.96 ± 37.16 mg/dL, 261.29 ± 76.98 ng/dL, and 9.37 ± 1.44%, respectively, in T2DM cases, while the corresponding values were 95.06 ± 12.68, 90.75 ± 67.53, and 4.81 ± 0.88 in healthy controls. Conclusion: Increased levels of serum ferritin were seen in T2DM and significant correlation between blood sugar and serum ferritin was found.