Evaluation of relationship between markers of inflammation and blood pressure in subjects attending OPD in a tertiary care center in Chennai
Artigo
| IMSEAR
| ID: sea-218028
ABSTRACT
Background:
The incidence and prevalence of hypertension have been increasing steadily in the present era. Inflammation is a proven key factor in the pathogenesis of hypertension. C-reactive protein (CRP) is a known marker of vascular inflammation leading to hypertension. High-sensitivity CRP (hs-CRP) is a sensitive marker of assessment of inflammatory changes before the rise in CRP. Aims andObjectives:
The goal of this study was to decipher the stage at which inflammation starts related to changes in hypertension using CRP as well as hs-CRP. Materials andMethods:
This is a cross-sectional study which included 120 individuals, who were subdivided into three groups - Normotensive 40, pre-hypertensive 40, and hypertensive. JNC classification was used for the categorization of blood pressure. hs-CRP was analyzed as per the principle of ELISA.Results:
There was a significant difference in hs-CRP between normotensive and hypertensive. A strong association between hypertension, CRP, and hs-CRP was found.Conclusion:
hs-CRP is a sensitive marker for early assessment of inflammatory components in hypertension.
Texto completo:
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Índice:
IMSEAR (Sudeste Asiático)
Ano de publicação:
2023
Tipo de documento:
Artigo
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