Secondary immune defects in non-Hodgkin's lymphoma.
Artigo
em Inglês
| IMSEAR
| ID: sea-22045
ABSTRACT
Changes in the humoral, cellular and phagocytic components of the immune system were investigated in 44 biopsy proven, untreated patients of non-Hodgkin's lymphoma (NHL). There was significant decrease in the total lymphocyte number, their subsets (T and B) and the T helper (T mu) population. Impaired leukocyte migration inhibition response and DNA synthesis following stimulation by phytohaemagglutinin were noted. Significant reduction of serum IgA was found in patients of both diffuse and nodular NHL. Phagocytic activity and nitroblue tetrazolium (NBT) reduction were unaltered, but chemotaxis was significantly reduced and bactericidal activity showed variable results.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Linfoma não Hodgkin
/
Humanos
/
Imunoglobulina A
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Imunoglobulina G
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Imunoglobulina M
/
Subpopulações de Linfócitos
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Imunidade Celular
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Contagem de Leucócitos
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Formação de Anticorpos
/
Neutrófilos
Idioma:
Inglês
Ano de publicação:
1992
Tipo de documento:
Artigo
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