Neutralization potency of Russell's viper venom toxoid antivenom, as compared with standard antivenom.
Artigo
em Inglês
| IMSEAR
| ID: sea-22090
ABSTRACT
Rabbits were immunized with gamma (gamma) irradiated Russell's viper venom toxoid, adsorbed to aluminium phosphate adjuvant. Antibody (raised against toxoid inoculation) titer was compared to a commercial antivenom on the basis of its ability to neutralize hemorrhagic, necrotic and lethal effects of viper venom. Toxoid immunization (on day 0, 15 and 30) produced antivenom which showed approximately one-third antilethal, half antihemorrhagic and antinecrotic titers as compared to those of the commercial hyperimmunized, concentrated horse antivenom.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Coelhos
/
Toxoides
/
Venenos de Víboras
/
Testes de Neutralização
/
Antivenenos
/
Hemorragia
/
Dose Letal Mediana
/
Animais
/
Camundongos
/
Necrose
Idioma:
Inglês
Ano de publicação:
1992
Tipo de documento:
Artigo
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