Comparative Study of Dexmedetomidine vs Esmolol for Attenuation ofStress Responses to Laryngoscopy and Endotracheal intubation.

ABSTRACT

Background: Endotracheal intubation is gold standard of general anaesthesia. But it hasdisadvantages of initiation of stress response to laryngoscopy and intubation. To alleviate itwe have used Dexmedetomidine & Esmolol.MethodsGroup E - Inj. Esmolol (1.0 mg/kg) in 10 ml normal saline two minutes before inductionGroup D – Inj. Dexmedetomidine (1μg/kg) in 10 ml normal saline over 10 minutes prior toinduction.Results and conclusion: both the drugs effectively supress stress response but Dexmedetomidine is better than Esmolol