Identification of rare atypical BCR-ABL1 transcript: A case report
Indian J Pathol Microbiol
;
2023 Sept; 66(3): 624-626
Artigo
| IMSEAR
| ID: sea-223496
ABSTRACT
CML is characterized by the presence of a BCR-ABL1 fusion transcript. Several guidelines have been published for its detection and molecular monitoring. Here, a case is described of chronic myeloid leukemia presenting in the blast phase with a rare variant transcript, with a discussion on possible red flags in its detection and genetic testing and description of the patient's clinical characteristics. This case highlights the pitfalls of using real-time quantitative reverse-transcription polymerase chain reaction (RQ-PCR) for diagnosis of CML, especially when the clinical picture and the test results are discordant.
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Índice:
IMSEAR (Sudeste Asiático)
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2023
Tipo de documento:
Artigo
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