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Anthropometric and Pubertal Outcomes in Girls With Classical Congenital Adrenal Hyperplasia
Indian Pediatr ; 2022 Jul; 59(7): 535-538
Artigo | IMSEAR | ID: sea-225349
ABSTRACT

Objective:

To evaluate the anthropometric and pubertal outcomes, over a spectrum of treatment regimens and compliance.

Methods:

We reviewed records of the patients with classical CAH seen at the endocrinology clinic of a tertiary care center between 1995 and 2016.

Results:

25 females were included in the study, the majority (80%) with simple virilizing variant. All patients had genital ambiguity since birth, yet 40% (10/25) presented much later with menstrual complaints. All patients received hydrocortisone, but some switched to dexamethasone (n=7) or prednisolone (n=4). 7/9 (77.9%) girls who achieved target height, were on hydrocortisone. Menarche occurred with corticosteroid treatment in 60% (15/25) patients at a median (IQR) age of 16 (12-22) years.

Conclusion:

Hydrocortisone seems to have a beneficial effect on linear growth. Once target height is achieved, dexamethasone may be considered as an alternative.

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Revista: Indian Pediatr Ano de publicação: 2022 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Revista: Indian Pediatr Ano de publicação: 2022 Tipo de documento: Artigo