Association of Lewis blood group with ischaemic heart disease.
Artigo
em Inglês
| IMSEAR
| ID: sea-22775
ABSTRACT
A total of 96 patients (74 males and 22 females) with ischaemic heart disease (IHD) who presented at a hospital in north India for cardiac bypass surgery, percutaneous coronary angioplasty or unstable angina were investigated for Lewis blood group phenotypes. A hundred and four normal healthy blood donors matched for age and sex served as controls. Lewis blood group typing was carried out on red cells using saline haemagglutination technique in a test tube with monoclonal antisera. 29.1 per cent of IHD patients had Le(a-b-) phenotype compared to 9.6 per cent of controls (P < 0.01). The relative risk of IHD for Le(a-b-) phenotype was found to be highly significant (risk = 3.87). We conclude that there is an increased frequency of Le(a-b-) phenotype among Indian patients with IHD.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Masculino
/
Fatores de Risco
/
Isquemia Miocárdica
/
Adulto
/
Antígenos do Grupo Sanguíneo de Lewis
/
Pessoa de Meia-Idade
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Idioma:
Inglês
Ano de publicação:
1999
Tipo de documento:
Artigo
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