A flowcytometric study of CD4+ & CD19+ cell lymphopenia in patients with alopecia areata.
Artigo
em Inglês
| IMSEAR
| ID: sea-26033
ABSTRACT
Twenty five patients with alopecia areata and 20 healthy controls were studied by flowcytometry employing direct two colour immunofluorescence in erythrocyte lysed whole blood. A significant reduction was observed in helper/inducer (CD4+) lymphocytes (29.4 +/- 7.4 vs 39.45 +/- 8.0, P < 0.01) and B (CD 19+) lymphocytes (11.04 +/- 6.57 vs 15.0 +/- 5.05, P < 0.01) in comparison with healthy controls. Decrease in T-lymphocytes (CD3+) and suppressor/cytotoxic (CD8+) was not significant and activated (HLADR+) lymphocytes and natural killer cells (CD16+ and CD56+) were within normal limits. Our findings suggest a significant T helper (CD4+) and B (CD19+) cell lymphopenia in alopecia areata.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Masculino
/
Antígenos CD4
/
Estudos de Casos e Controles
/
Criança
/
Pré-Escolar
/
Adolescente
/
Antígenos CD19
/
Adulto
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Ano de publicação:
1996
Tipo de documento:
Artigo
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