Correlation of biological activity (therapeutic and toxic) with solvochromic properties of metronidazole, emetine hydrochloride and diloxanide furoate.
Indian J Biochem Biophys
;
1995 Oct; 32(5): 302-7
Artigo
em Inglês
| IMSEAR
| ID: sea-26778
ABSTRACT
Goat blood, when incubated for different periods with diloxanide furoate, metronidazole and emetine hydrochloride, underwent changes in fatty acid constituents and their peroxidation products measured as malonaldehyde. These findings, together with the changes noted in the drug-lipid partition coefficient, are discussed in an attempt to correlate the lipid constitution and biological activity of the drugs.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fosfolipídeos
/
Solubilidade
/
Cabras
/
Emetina
/
Amebicidas
/
Furanos
/
Animais
/
Metronidazol
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
1995
Tipo de documento:
Artigo
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