Role of fatty acid binding protein in the modulation of inhibitory effect of fatty acids on fatty acid synthase and ATP-citrate lyase in developing human brain.
Indian J Biochem Biophys
;
1998 Oct; 35(5): 296-302
Artigo
em Inglês
| IMSEAR
| ID: sea-26855
ABSTRACT
Inhibition of the activities of fatty acid synthase and ATP-citrate lyase (ATP-CL) by fatty acids and their CoA esters has been studied. Purified fatty acid binding protein from human fetal brain reverses this inhibition. This protein also activates the enzyme when added alone. ATP-citrate lyase and fatty acid synthase activity gradually increased with the advancement of gestation showing a relationship between high demand of fatty acid synthesis in developing brain and supply of its precursors.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
ATP Citrato (pro-S)-Liase
/
Humanos
/
Proteínas de Transporte
/
Ácido Graxo Sintases
/
Ácidos Graxos
/
Desenvolvimento Embrionário e Fetal
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
1998
Tipo de documento:
Artigo
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