Antidiabetic and hypolipidemic effects of S-methyl cysteine sulfoxide isolated from Allium cepa Linn.
Indian J Biochem Biophys
;
1995 Feb; 32(1): 49-54
Artigo
em Inglês
| IMSEAR
| ID: sea-27384
ABSTRACT
S-methyl cysteine sulphoxide (SMCS), a sulphur containing amino acid isolated from onion (Allium cepa Linn) showed antidiabetic and antihyperlipidemic effects. Oral administration of SMCS daily at a dose of 200 mg/kg body weight for a period of 45 days to alloxan diabetic rats controlled significantly their blood glucose and lipids in serum and tissues and altered the activities of liver hexokinase, glucose 6-phosphatase and HMG CoA reductase towards normal. The above effects of SMCS were comparable to those of glibenclamide and insulin.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Allium
/
Masculino
/
Ratos Sprague-Dawley
/
Cisteína
/
Diabetes Mellitus Experimental
/
Hipoglicemiantes
/
Animais
/
Hipolipemiantes
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
1995
Tipo de documento:
Artigo
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