Early and long-term effects of chronic low-dose radiation and coenzyme Q diet on the proliferation of rat spleen T cells.
Indian J Biochem Biophys
;
1998 Apr; 35(2): 103-7
Artigo
em Inglês
| IMSEAR
| ID: sea-27653
ABSTRACT
Chronic whole-body irradiation (0.43 cGy/day; total doses 11, 23, and 35 cGy) caused non-monotonous long-term disturbances in rat splenic T lymphocytes proliferation. Immunosuppression observed after chronic exposure had no correlation with the splenic cell number and the decrease in the fluorescence intensity of Hoechst 33258-DNA complex in T lymphocytes. Small, but significant radioprotection was observed with Coenzyme Q diet immediately after irradiation. These results indicate that the changes in T cell immunity, T cell viability, and T cell DNA state after exposure to low dose radiation are not interrelated.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ratos
/
Baço
/
Masculino
/
Ativação Linfocitária
/
Linfócitos T
/
Irradiação Corporal Total
/
Ubiquinona
/
Ratos Wistar
/
Dieta
/
Relação Dose-Resposta à Radiação
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
1998
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS