Cellular AATF gene: armour against HIV-1.
Indian J Biochem Biophys
;
2007 Oct; 44(5): 276-8
Artigo
em Inglês
| IMSEAR
| ID: sea-27966
ABSTRACT
Outcome of HIV-1 infection at the cellular level is decided by the orchestrated balance that exists between cellular nucleic acid-based adaptive immune mechanism involving non-coding micro RNAs (miRNAs) and offensive tactics of HIV-1 to suppress this host cellular immunity. In this context, the review explains the importance of a novel miRNA encoded exclusively and conspicuously by HIV-1 genome that has the ability to specifically target cellular AATF gene recognized to play a crucial role in the maintenance of adaptive immunity at nucleic acid level against HIV-1 invasion.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Proteínas Repressoras
/
Fatores de Transcrição
/
Humanos
/
Fenômenos Fisiológicos Celulares
/
HIV-1
/
Apoptose
/
MicroRNAs
/
Proteínas Reguladoras de Apoptose
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
2007
Tipo de documento:
Artigo
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