INH induced status epilepticus: response to pyridoxine.
Indian J Chest Dis Allied Sci
;
2006 Jul-Sep; 48(3): 205-6
Artigo
em Inglês
| IMSEAR
| ID: sea-30352
ABSTRACT
Isoniazid is an effective and widely used drug in tuberculosis treatment. The administration of toxic amounts of INH causes recurrent seizures, profound metabolic acidosis, coma and even death but therapeutic dose of isoniazid is a very rare cause of seizures. We present a case of 44-year-old HIV positive African-American female who was recently started on a preventive dose of INH after being found purified protein derivative (PPD) positive. She developed status-epilepticus that did not respond to most of the antiepileptics. As soon as she received intravenous pyridoxine, the seizures terminated abruptly.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Piridoxina
/
Estado Epiléptico
/
Complexo Vitamínico B
/
Humanos
/
Masculino
/
Síndromes Neurotóxicas
/
Isoniazida
/
Pessoa de Meia-Idade
/
Antituberculosos
Idioma:
Inglês
Revista:
Indian J Chest Dis Allied Sci
Ano de publicação:
2006
Tipo de documento:
Artigo
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