Towards a malaria vaccine: riding the rollercoaster between unrealistic optimism and lethal pessimism.
Southeast Asian J Trop Med Public Health
;
1992 Dec; 23(4): 656-71
Artigo
em Inglês
| IMSEAR
| ID: sea-30823
ABSTRACT
Activity in many laboratories over the past decade has resulted in many vaccine candidates nearing clinical trials. These include several antigens from the sporozoite stage; merozoite surface antigens MSA1 and MSA2, RESA, the rhoptry proteins RAP-1 and RAP-2 from the asexual blood stage; the pfs25, pfg45 and pfg230 from the ookinete and gamete stages. This progress in the identification of potential vaccine candidates now highlights a series of scientific, developmental, economic and operational problems the solutions to which will be as critical to the development of a vaccine as the cloning and expression of parasite genes.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Plasmodium
/
Humanos
/
Vacinas Protozoárias
/
Animais
/
Malária
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1992
Tipo de documento:
Artigo
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