Indirect hemagglutination antibodies against Burkholderia pseudomallei in normal blood donors and suspected cases of melioidosis in Malaysia.
Southeast Asian J Trop Med Public Health
;
1996 Jun; 27(2): 263-6
Artigo
em Inglês
| IMSEAR
| ID: sea-31081
ABSTRACT
Interpretation of the indirect hemagglutination test (IHA) for melioidosis in endemic areas is difficult because of the presence of antibodies in apparently healthy individuals. Fifty-three out of 200 healthy blood donors in Malaysia showed positive antibody titers (> or = 1 40) against Burkholderia pseudomallei. Seven percent had an IHA titer of 1 40, 11% had an IHA titer of 1 80 while 8.5% had a titer > or = 1 160. Out of 258 sera sent for melioidosis serology, 7% of the patients had an IHA titer of 1 40, 9% had an IHA titer of 1 80 while 20% had an IHA titer of > or = 1 160. If a titer of > or = 1 80 is taken as cut off point for positivity, 29% of the patients had positive melioidosis serology. Increasing the positivity threshold may jeopardize the sensitivity of the test. A more specific and sensitive test is needed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Doadores de Sangue
/
Humanos
/
Testes de Hemaglutinação
/
Programas de Rastreamento
/
Prevalência
/
Reprodutibilidade dos Testes
/
Sensibilidade e Especificidade
/
Burkholderia pseudomallei
/
Doenças Endêmicas
/
Malásia
Tipo de estudo:
Estudo diagnóstico
/
Estudo de prevalência
/
Estudo prognóstico
/
Estudo de rastreamento
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1996
Tipo de documento:
Artigo
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