Therapy related acute non-lymphocytic leukemia: report of 4 cases.
Southeast Asian J Trop Med Public Health
;
1985 Sep; 16(3): 421-30
Artigo
em Inglês
| IMSEAR
| ID: sea-31472
ABSTRACT
Four cases of acute myelodysplastic-non-lymphocytic leukemia secondary to cytotoxic agents were reported. Primary diseases were breast cancer (1 patient), ovarian cancer (2 patients) and multiple myeloma (1 patient). All except one (with multiple myeloma) were in clinical remission of their primary diseases. Common cytotoxic agent used was melphalan. Median total drug dose and median latent period from diagnosis of primary diseases were 1299 mg and 63 months respectively. None with the exception of one received specific treatment. All died except one who is in a very poor condition. Survival from the diagnosis of hematologic diseases ranged from 3-9 months. Clinical features, cytogenetic findings, pathogenetic mechanism and risk of the disease were briefly discussed.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Ovarianas
/
Radioterapia
/
Neoplasias da Mama
/
Feminino
/
Humanos
/
Leucemia
/
Leucemia Induzida por Radiação
/
Doença Aguda
/
Aberrações Cromossômicas
/
Adulto
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1985
Tipo de documento:
Artigo
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