Lupus anticoagulant in Thai systemic lupus erythematosus patients.
Southeast Asian J Trop Med Public Health
;
1993 ; 24 Suppl 1(): 241-5
Artigo
em Inglês
| IMSEAR
| ID: sea-31523
ABSTRACT
In the past decade, interest in the potential clinical significance of lupus anticoagulant (LA) has grown tremendously. Recent reviews from the Western countries have found an average frequency of 34% for LA in patients with systemic lupus erythematosus (SLE). By using various laboratory procedures, namely, standard and diluted activated partial thromboplastin time, kaolin clotting time, tissue thromboplastin inhibition test and platelet neutralization test, we found the frequency of LA in 91 consecutive Thai SLE patients to be 17.5%, compared with 0.8% in the age-matched normal control population. The presence of LA was significantly associated with disease activity (p = 0.01). A statistically significant association was also observed between the presence of LA and convulsive disorders (p = 0.04), thrombocytopenia (p = 0.001) and autoimmune hemolytic anemia (p = 0.02).
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Convulsões
/
Tailândia
/
Trombocitopenia
/
Feminino
/
Humanos
/
Masculino
/
Estudos de Casos e Controles
/
Estudos Prospectivos
/
Adolescente
/
Inibidor de Coagulação do Lúpus
Tipo de estudo:
Estudo observacional
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
1993
Tipo de documento:
Artigo
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