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Epidemic of fever of unknown origin in rural Thailand, caused by influenza A (H1N1) and dengue fever.
Southeast Asian J Trop Med Public Health ; 1990 Mar; 21(1): 61-7
Artigo em Inglês | IMSEAR | ID: sea-31727
ABSTRACT
In the late summer (rainy season) of 1987, a sharp outbreak of fever of unknown origin (FUO) in rural southern Thailand was investigated by a field epidemiology team. In a random survey of households, 40 percent of the children and 20 percent of adults were reported to have had febrile illnesses within the last month. There was at least one death, possibly from Reye's syndrome. Testing 34 pairs of acute and convalescent sera showed significant HI antibody titer rises to influenza A (Taiwan/(H1N1) (9 cases) and dengue virus (12 cases). Testing 79 single sera with the antibody capture ELISA test for dengue, revealed that 23 percent had high titers in the IgM serum fraction suggesting recent infection. There were also six antibody titer rises to coxsackie B viruses, three from well controls. Dengue has previously been observed as a cause of FUO in rural areas in the tropics, but finding a combined epidemic of dengue and influenza was unexpected. With cooperative villagers, adequate personnel and laboratory support, especially the antigen capture ELISA test for dengue infections, it is feasible to successfully investigate disease outbreaks with serologic methods in remote villages.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Vírus da Influenza A / População Rural / Tailândia / Infecções por Togaviridae / Feminino / Humanos / Masculino / Ensaio de Imunoadsorção Enzimática / Vírus Chikungunya / Surtos de Doenças País/Região como assunto: Ásia Idioma: Inglês Revista: Southeast Asian J Trop Med Public Health Ano de publicação: 1990 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Vírus da Influenza A / População Rural / Tailândia / Infecções por Togaviridae / Feminino / Humanos / Masculino / Ensaio de Imunoadsorção Enzimática / Vírus Chikungunya / Surtos de Doenças País/Região como assunto: Ásia Idioma: Inglês Revista: Southeast Asian J Trop Med Public Health Ano de publicação: 1990 Tipo de documento: Artigo