Contrast-induced nephropathy.
Indian Heart J
;
2008 Mar-Apr; 60(2): 133-8
Artigo
em Inglês
| IMSEAR
| ID: sea-3195
ABSTRACT
Contrast-induced nephropathy (CIN) is a fairly common yet under-recognized clinical condition in the interventional cardiological practice. A 25% or more than 0.5 mg/dl rise of serum creatinine is generally accepted as defining CIN. The most important risk factors for CIN are pre-existing renal disease, volume of contrast media, nature of contrast media, and diabetes mellitus. Among the various postulated pathophysiological mechanisms for the precipitation of CIN, intra-renal vasoconstriction, and oxidative tubular injury are the best documented. Effective strategies to prevent CIN include adequate peri-procedural hydration with normal saline, use of N-acetylcysteine, keeping the volume of contrast media as low as feasible, and avoiding high-osmolal ionic contrast media. However, more efficient and cost-effective strategies are being developed and the search for the ideal contrast media is still on.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Vasoconstrição
/
Humanos
/
Endotélio Vascular
/
Fatores de Risco
/
Meios de Contraste
/
Creatina
/
Nefropatias
/
Óxido Nítrico
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian heart j
Ano de publicação:
2008
Tipo de documento:
Artigo
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