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Schistosoma mansoni: relocation of parasites to lungs from hepatic portal system in rodents.
Southeast Asian J Trop Med Public Health ; 1997 Sep; 28(3): 581-7
Artigo em Inglês | IMSEAR | ID: sea-31993
ABSTRACT
The prevalence and development of adult worms in the lungs of mice and gerbils infected with Schistosoma mansoni was investigated. All infected BALB/c mice harbored the schistosomes in their lungs at 10-12 weeks post-infection, showing the distinct relocation of adult worms to the lungs, from the hepatic portal system. The male and female flukes from lungs of BALB/c mice were significantly smaller than those from livers. The percentage of gravid females in lungs was considerably lower than that in the livers. The number of eggs recovered from lungs of BALB/c mice and gerbils having lung female worms, however, was higher than that from animals without lung females, indicating egg deposition of lung females. The number of eggs detected in the brains correlated well with the number of eggs from the lungs in BALB/c and ICR mice. Out of 119 infected gerbils at 8 weeks post-infection, only two animals had egg-emboli in the brain vessels, although many eggs embolized in the lungs of those animals. These data suggest that transfer of worms to the lungs from livers involves reduction of worm recovery from the portal circulation, and also pulmonary pathology of the disease.
Assuntos
Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Contagem de Ovos de Parasitas / Sistema Porta / Schistosoma mansoni / Fatores de Tempo / Esquistossomose mansoni / Feminino / Masculino / Gerbillinae / Modelos Animais de Doenças / Pulmão Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Southeast Asian J Trop Med Public Health Ano de publicação: 1997 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Contagem de Ovos de Parasitas / Sistema Porta / Schistosoma mansoni / Fatores de Tempo / Esquistossomose mansoni / Feminino / Masculino / Gerbillinae / Modelos Animais de Doenças / Pulmão Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Southeast Asian J Trop Med Public Health Ano de publicação: 1997 Tipo de documento: Artigo