Prevalence of human cytomegalovirus (HCMV) gB genotypes in Thai patients.
Southeast Asian J Trop Med Public Health
;
2007 Sep; 38(5): 835-40
Artigo
em Inglês
| IMSEAR
| ID: sea-32016
ABSTRACT
Human cytomegalovirus (HCMV) infection can cause asymptomatic to symptomic diseases leading to morbidity and mortality especially in immunocompromized patients. One factor of the difference in clinical outcome is the distinction of HCMV strain. As HCMV glycoprotein (g)B plays an important role in viral entry and neutralizing antibody induction, HCMV gB genotypes were determined in 161 clinical specimens containing HCMV-DNA obtained from patients at King Chulalongkorn Memorial Hospital, Bangkok, Thailand during the year 2000 and 2004. Of the 113 (70%) samples that were able to be genotyped, mixed gB genotype was demonstrated in 35%, followed by gB1 (33%), gB3 (15%), gB2 (11%), and untyped (7%); gB4 was not detected. The distribution of HCMV gB genotypes between genders was not significantly different. Mixed gB genotype (35%) was found in HIV- infected patients.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Tailândia
/
Polimorfismo de Fragmento de Restrição
/
Feminino
/
Humanos
/
Masculino
/
Infecções por HIV
/
Proteínas do Envelope Viral
/
Reação em Cadeia da Polimerase
/
Prevalência
/
Hospedeiro Imunocomprometido
Tipo de estudo:
Estudo de prevalência
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Southeast Asian J Trop Med Public Health
Ano de publicação:
2007
Tipo de documento:
Artigo
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